Vaping and electronic cigarettes (e-cigarettes) are battery-operated devices which produce an aerosolized mixture from a solution of concentrated nicotine, flavoring chemicals, and other substances to be inhaled by the user. These devices have exploded in popularity over the last several years, largely due to aggressive marketing and advertising that include unsubstantiated claims of e-cigarettes as “healthier” than conventional cigarettes. This presentation will highlight the current scientific evidence on electronic cigarettes and the impact on youth tobacco use, health and public health effects.